What Happens During a Biopsy Procedure?
A biopsy procedure is used to remove
suspicious material for examination. For people who have not had a biopsy before, it can be a bit alarming to
hear that one has been requested. Knowing the details of what to expect can make
people feel more prepared, allowing them to relax for the procedure so that it will go smoothly. In all
cases, biopsy results should be discussed with a doctor to ensure that the
patient knows what the results mean and what sort of response should be taken.
Before a biopsy procedure takes place, a doctor must determine
that the patient needs one. A physical examination may reveal an area of
concern, such as a patch of skin which has changed color, or a lump in the soft
tissue. A biopsy may also be requested
if a medical imaging study reveals an irregularity, or if a biopsy would assist a doctor in arriving at a
diagnosis.
The first step in a biopsy procedure is preparation of the site and the
patient. The site is typically swabbed and washed so that it is sterile, and in
areas where there is hair, the site may be shaved. Next, a local anesthetic is
injected so that the patient will not experience pain. In some cases, the
patient may be offered antianxiety medication to relax for the biopsy. For certain biopsies, the patient may
be put under a general anesthetic.
In biopsies where the patient is anesthetized, anesthesia is used for the
purpose of a surgical biopsy, in which a
doctor cuts into the body to remove a sample from the area of interest. This
technique is less common with the advent of several types of needle biopsy, ranging from fine needle aspiration to
vacuum-assisted biopsy, in which a large
needle is inserted into the area of interest and used to remove a sample from a
conscious patient. If the area being biopsied is on the skin, a scalpel will be
used to scrape off a sample.
The biopsy may be taken with the
assistance of medical imaging such as ultrasound. The medical imaging is used
to correctly identify the area of interest so that the sample is taken from the
right place. In a wire-guided biopsy, the imaging is used while fine wires are
placed to mark the area which needs to be biopsied, and a surgeon uses the
wires as a guide for a surgical biopsy.
Some procedures may require the use of endoscopic probes which are inserted
into the body to generate an image, allowing the doctor to clearly see the site
which needs to be biopsied.
If the patient is conscious, he or she will need to hold very still during the biopsy procedure,
and it may be necessary to assume a particular position. The biopsy should not be painful, because of the
local anesthetic, but it can be uncomfortable. Especially in cases where probes
are used, discomfort is common for conscious patients, as for example in an
endoscopic biopsy of the esophagus.