There should be a national and governmental context for planning of CRC screening. The programme
needs political support with sustainable funding to succeed. If appropriate structures in the healthcare
system are lacking, screening should not be implemented until they are developed, for example using
the implementation phase to build up the needed structures.
It is essential that the programme is integrated into the healthcare system and is accepted by both
the population and health professionals involved in the diagnostic process for CRC. Organisation of the
screening programme should integrate the structures of the entire health care system appropriately
and it should comply with national guidelines and protocols. Within the organisational framework of
the programme, the target population should be defined as well as the frequency of screening. Provisions
should be made for the financing of the programme, including evaluation costs.
The professional and organisational managers of a screening programme must have sufficient authority
and autonomy, including an identified budget and sufficient control over the use of resources to
effectively control the quality, effectiveness and cost-effectiveness of the programme and the screening
service. The institutional structure must facilitate effective management of quality and performance.
Process and outcome indicators should be constantly evaluated to serve the needs of the individual
and the health service.
Adequate protection of all data should be ensured, following requirements set by European directives
concerning data protection and national privacy legislation.
Local conditions at the start of a programme
Before implementation of a screening programme, an inventory of baseline conditions including information
on opportunistic screening rates, background CRC incidence rates and availability of endoscopic
resources should be made.
In order to run a successful programme, adequate resources, in terms of both staff and facilities must
be available, and an adequate infrastructure must be in place.
Colonoscopy is the final common denominator of all the CRC screening strategies. Therefore, as the
implementation of any form of population screening for CRC will place greater demands on colonoscopy
resources, the feasibility of CRC screening also depends on the availability of colonoscopy services.
There may also be limitations to access for subjects in rural or remote areas and in the public
health sector. Clearly, CRC screening is only feasible if access can be guaranteed to individuals who
participate in screening.
In many European countries, CRC early detection activity exists in some form, e.g. testing personally
initiated by patients, or as a component of private health care. According to the findings of a recent
survey conducted in 10 European countries and in Canada, about 10% of colonoscopies are performed
for screening (Burnand et al. 2006). However a wide variation was found in the occurrence
and in the appropriateness of the exams. The inappropriateness rates ranged between 0% and 50%.
Similarly the proportion of colonoscopies performed following clinical indications which were judged to be inappropriate was about 25%, suggesting overuse of the exam. Even if screening exams should be
delivered within dedicated sessions (see also Chapter 5), promoting a more appropriate use of colonoscopy
might therefore increase quality of care and favour an efficient use of available resources. As
suggested by simulations conducted in the US (Seeff et al. 2004) a more efficient use of colonoscopy
resources may result in an increase in the capacity to meet the demand of screening-induced colonoscopies.
It is unlikely, however, that simply providing funds to increase existing activity will enable the programme
or screening policy to be successful. In parallel with introducing the general principles of organised
screening, governments should consider the introduction of administrative measures (i.e. not
paying for unnecessary exams) and implementing educational interventions aimed at enhancing appropriateness
of colonoscopy referrals. In some countries, re-allocation of resources already used for
opportunistic screening activities will be sufficient to cover the entire target population within a defined
screening interval.
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